H5 avian and H9 swine influenza virus haemagglutinin structures: possible origin of influenza subtypes

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H5 avian and H9 swine influenza virus haemagglutinin structures: possible origin of influenza subtypes.

There are 15 subtypes of influenza A virus (H1-H15), all of which are found in avian species. Three caused pandemics in the last century: H1 in 1918 (and 1977), H2 in 1957 and H3 in 1968. In 1997, an H5 avian virus and in 1999 an H9 virus caused outbreaks of respiratory disease in Hong Kong. We have determined the three-dimensional structures of the haemagglutinins (HAs) from H5 avian and H9 sw...

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Anticipating the Prevalence of Avian Influenza Subtypes H9 and H5 in Live-Bird Markets

An ability to forecast the prevalence of specific subtypes of avian influenza viruses (AIV) in live-bird markets would facilitate greatly the implementation of preventative measures designed to minimize poultry losses and human exposure. The minimum requirement for developing predictive quantitative tools is surveillance data of AIV prevalence sampled frequently over several years. Recently, a ...

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Multiplex Reverse Transcriptase-PCR Assay for Typing and Subtyping of Influenza A (H5 & H9) Virus in Iran

Avian influenza virus (AIV) infection is a major cause of bird or human mortality and morbidity, therefore the rapid identification of the virus is of important clinical and epidemiological implication. Methods: A multiplex Reverse Transcriptase PCR (RT-PCR) was optimized for the detection of influenza A virus and the H5 and H9 subtypes. The influenza type A specific primers were directed to t...

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Risk Assessment of the Introduction and Spread of Highly Pathogenic Avian Influenza Viruses (H5-Subtypes) Via Migratory Birds in Iran

Background and Objectives: HPAI has economic and public health importance. Aquatic and shore migratory birds are the main reservoirs and the cause of the spread of viruses across countries. The aim of study was risk assessment of the spread of the avian influenza H5 viruses.   Methods: In this qualitative study, structured interviews and focus group discussions were used to assess the risk of...

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ژورنال

عنوان ژورنال: The EMBO Journal

سال: 2002

ISSN: 1460-2075

DOI: 10.1093/emboj/21.5.865